The PHRED Program has been funded by the Public Health Branch of the Ontario Ministry of Health. This program operates at six health units across the province. One role of the PHREDs is to conduct clinically-relevant research into public health, health promotion and primary care, and to foster evidence-based practice and policy-making. One initiative within PHRED is the Effective Public Health Practice Project, an initiative involving public health researchers, practitioners, and policy-makers from across the province. The Effective Public Health Practice Project conducts systematic reviews that evaluate the effectiveness of relevant interventions. This project, coordinated from the Hamilton-Wentworth PHRED, has produced sixteen reviews and summaries on the effectiveness of interventions for the Ontario Ministry of Health, Public Health Branch. Work is ongoing in this field.